Semen Analysis
What is Semen Analysis?
Semen analysis is a key diagnostic tool to evaluate male fertility. It assesses the quantity and quality of sperm, including parameters like sperm concentration, motility, and morphology. The results provide valuable information about one’s reproductive capabilities and assist in determining the fertility potential.
Cryomate offers comprehensive semen analysis at our state-of-the-art andrology labs, performed by fertility specialists using advanced technology — giving you a clear, accurate picture of your sperm health.
What are the main parameters typically checked in a semen analysis?
Sperm Concentration (Sperm Count)
A normal sperm concentration is considered to be at least 15 million sperm per milliliter of sample. The total number of sperm in the entire ejaculate (sperm count) should be at least 39 million.
Sperm Motility
Refers to the ability of the sperm to move forward and through the female reproductive system and fertilize the egg. The percentage of progressively motile sperm (those moving forward) should be at least 32%. Total motility (including all types of movement) should be at least 40%.
Sperm Morphology (Shape)
At least 4% of sperm cells in the sample should have normal morphology (normal shape). Abnormalities in shape may impact the ability of sperm to travel, penetrate, and fertilize an egg.
Volume of Semen Sample
Sperm volume refers to the amount of semen one produces during ejaculation. It is measured in milliliters and indicates the total liquid content released from the reproductive system at the time of ejaculation. A normal volume is considered to be 1.5 milliliters or more.
Reference ranges align with WHO Laboratory Manual for the Examination and Processing of Human Semen, 6th edition (2021).
Why is it important to evaluate the sperm quality?
Infertility is a growing concern, affecting 1 out of every 6 couples globally, with male-factor infertility estimated to contribute to approximately 50% of cases.
While there are all sorts of reasons behind the fertility struggle, sperm quality emerges as a pivotal predictor of fertility. Here are the main reasons to stay up-to-date with your sperm quality:
Detecting potential reproductive issues early on contributes to the prevention and management of conditions, and can result in more effective and less intrusive treatments.
Reproductive health is interconnected with overall health and as such can affect both reproductive and general well-being. Regular evaluations can provide a holistic view of one’s health.
Assisting in maximizing the timing for conception, making well-informed decisions, including exploring options for fertility preservation, and seeking assistance when necessary.
WHAT AFFECTS SPERM QUALITY?
Several factors can influence sperm quality:
Age
As men age, their sperm quality gradually declines. This decline is characterized by reduced motility and increased DNA fragmentation. Research indicates that sperm motility decreases by approximately 0.8% per year, while the percentage of sperm with normal morphology decreases by 0.2–0.9% annually. Over a 20-year period, this can result in a 4–18% decline in overall sperm quality. Additionally, aging sperm is associated with higher rates of DNA fragmentation and an increased likelihood of genetic mutations, which have been linked to conditions such as schizophrenia and autism. To address these potential issues, freezing sperm at a younger age is often recommended as a proactive measure.
Lifestyle Choices
Certain lifestyle choices can significantly impact sperm quality. Behaviors such as smoking, excessive alcohol consumption, and drug use have been shown to negatively affect sperm health. Additionally, a diet lacking essential nutrients can impair both sperm production and performance. Prioritizing a healthier lifestyle can help support and maintain optimal reproductive health.
Environmental Factors
Exposure to excessive heat, such as from hot baths, saunas, or tight-fitting clothing, can negatively impact sperm production. Additionally, environmental toxins, pesticides, and pollutants may compromise sperm quality. Stress, a common factor in modern life, can also affect reproductive health. Taking steps to minimize exposure to environmental heat and toxins, as well as managing stress effectively, can help support healthy sperm production and overall reproductive health.
Medical & Genetic Reasons
Sexually transmitted infections (STIs), such as chlamydia or gonorrhea, can significantly impact fertility. These infections may disrupt the reproductive process, making it essential to prioritize sexual health and safety to maintain optimal reproductive function. On the genetic side, certain conditions and mutations can affect sperm production, morphology, and function, potentially leading to challenges with fertility.
It’s important to note that individual responses to these factors can vary. If there are concerns about fertility or sperm quality, consulting with a healthcare professional or a reproductive specialist is advisable!
THE SEMEN ANALYSIS PROCESS
A semen analysis (SA) is conducted in a laboratory setting to assess various aspects of
sperm health. The process typically involves the following steps:
Preparation: Refrain from sexual activity for 2–7 days before the analysis to ensure an optimal sample.
Sample Collection: You will be provided with a sterile container to collect the sample. It’s important to avoid the use of lubricants, as they can affect the quality of the sperm. Be sure to collect the entire sample for accurate analysis.
Sample Handling: After collection, keep the sample at body temperature and deliver it to the lab within 60 minutes to maintain its integrity.
Initial Assessment: The lab technician will evaluate the volume, color, and viscosity of the sample. Normal semen is typically opaque with a gel-like consistency that liquefies within approximately 30 minutes.
Sperm Parameter Assessment: A portion of the sample will be examined under a microscope to assess various sperm parameters, including motility, count, and morphology.
Additional Testing: In some cases, further tests may be conducted, such as measuring the pH level of the sample or checking for the presence of white blood cells, which could indicate an infection.
Report and Insights: A detailed semen analysis report will be provided, offering insights into fertility potential and identifying any potential issues that may affect reproductive health.
Semen Analysis Pricing & Turnaround Time
Our semen analysis is available for $295, with results provided within 48-72 hours. To schedule an appointment or learn more, contact the Cryomate team at the location nearest you.
IS SPERM ANALYSIS COVERED BY INSURANCE?
Coverage varies by insurance plan. Check with your provider to confirm if it’s included and any out-of-pocket costs. If covered, expenses typically range from $100 to $300, depending on your deductible and copayment.
Our andrology labs
Indianapolis, IN320 North Meridian Street, Suite 606
Indianapolis, IN 46204
463.333.3530 ext. 2 | lab@cryomate.com
Nashville, TN1105 16th Ave S, Suite C
Nashville, TN 37212
463.333.3530 ext. 4 | TNdonor@cryomate.com
The team behind your results
Cryomate’s andrology lab is directed by Dr. Sheela Ali, PhD, HCLD, CC, TS(ABB) — an internationally recognized reproductive scientist, embryologist, and laboratory director with more than 18 years of experience in assisted reproductive technologies, andrology, reproductive tissue banking, and laboratory operations. Day-to-day laboratory operations are led by Larissa Volz, MS, whose graduate research focused specifically on how sperm interact with the female reproductive tract.
Cryomate holds CAP accreditation, FDA registration, and CLIA certification — among the most rigorous laboratory standards in the US. Every sample is handled with the care and scientific precision of a team dedicated entirely to reproductive biology and andrology.
Frequently Asked Questions
What is included in a semen analysis?
A standard semen analysis at Cryomate evaluates sperm concentration, total sperm count, progressive motility, total motility, morphology, and semen volume. Additional parameters such as viability may also be assessed depending on clinical need.
How much does a semen analysis cost?
Semen analysis at Cryomate is $295. This includes the full panel of WHO-standard parameters and a results report delivered to your referring physician within 48–72 hours.
How do I prepare for my semen analysis?
For the most accurate results, we recommend abstaining from ejaculation for 2–7 days before your appointment. Avoid alcohol, cannabis, and any non-prescribed medications for at least 5 days prior. On the day of your analysis, stay hydrated and avoid strenuous exercise
How long does it take to get semen analysis results?
Results are typically available within 48–72 hours of your appointment. Your physician’s office will receive a detailed report outlining each parameter alongside standard reference ranges.
Is semen analysis covered by insurance?
Coverage varies by insurance plan and the clinical reason for testing. We recommend contacting your provider directly to confirm your benefits. Our team can provide documentation to support your claim if needed.
What happens if my results are abnormal?
Abnormal results don’t necessarily mean infertility. Many parameters that fall outside standard reference ranges are treatable or manageable. After your test is completed, we will provide the results to your physician, who will review them with you and answer any questions regarding recommended follow-up or treatment options.
How is Cryomate’s semen analysis different from a standard lab?
Cryomate is a dedicated sperm bank and andrology lab — not a general diagnostic facility. Your sample is analyzed by fertility specialists who work with sperm exclusively, in a CAP-accredited, CLIA-certified environment built for this purpose. That specialization translates directly into more precise results and more informed guidance.
Cryomate is a CAP-accredited, FDA-registered, CLIA-certified sperm bank with andrology labs in Indianapolis, Indiana and Nashville, Tennessee.
